Newton’s Law of Gravitational Force (NLGF) based Machine Learning Technique for Uneven Illuminated Face Detection

A photo gallery is crucial for organizing your photos, presenting them in beautiful categories, and doing sophisticated memory searches. The photo gallery is portrayed in a vocabulary of nonlinear similarities to the prototype face image collection. One of the difficult research ideas for machine learning technologies is the maintenance of a photo gallery using facial recognition. Based on changes in the faces' appearance, faces are identified. This research proposes novel machine learning algorithms to recognize faces by characterizing the majority of discriminating local characteristics, which maximizes the dissimilarity between face photos of different persons and reduces the dissimilarity between features between face images of the same person. This method relies on Newton's third law of gravitational force to determine the relationship between pixels to extract the features of noisy accurately and efficiently, unevenly illuminated, and rotationally invariant face images

Design, Synthesis, Characterization of Geminal Bisphosphonates and Bioactivity Evaluation

Cancer is a deadly disease evading all human efforts to understand its etiology, prevention, and cure. In cancer, chronic myelogenous leukemia is one type. It is also known as chronic myeloid leukemia. It is a malignant cancer of the myeloid line of cells in the bone marrow that results in the uncontrolled growth of white blood cells in the bone marrow, bloodstream, and body tissues. Colorectal cancer is another type of cancer that occurs in the colon or rectum. Sometimes it is called colon cancer. Management of these cancers is highly difficult. In persuasion of our goal to synthesize cancer active compounds, the author accomplished the synthesis of substituted amino methylene bisphosphonates (3a-j) and studied their antitumor activity. © 2020 Author(s)

Synthesis and Cytotoxic Activity of Various alkyl 2-{di[(diethoxy phosphoryl) methyl]amino}ester Derivatives

We have been synthesized simple, efficient various alkyl 2-{di[(diethoxy phosphoryl) methyl]amino}ester derivatives by reacting amino acid esters 1(a-j), paraformaldehyde and two molar equivalents of diethyl hydrogenphosphonate (2) in tetrahydrofuran at 55-65 °C for 10 hrs. All the compounds 3(a-j) were assessed for cytotoxicity against some important types of human chronic myeloid leukemia cells (K-562) and human colon carcinoma cells (Colo-205) along with noncancerous human embryonic kidney cells (HEK-293). © 2020 Author(s)

Synthesis and Antimicrobial Activity of New α-Aminophosphonic Acid Esters

Synthesis ofnew-aminophosphonic acid esters (3a–l) was accomplished by the reaction of equimolar quantities of phenyl ethyl glycine and various aryl aldehydes with diethyl/ dimethylphosphite in dry toluene at reflux temperature. All the structures of the newly synthesized α-aminophosphonic acid esters (3a–l) were established by elemental analysis, and IR, 1H, 13C, 31P NMR and mass spectral data. The antimicrobial and antifungal activities of these compounds were evaluated and they exhibited significant activity.Keywords: Phenyl glycine ethyl ester, aryl aldehydes, diethyl/dimethylphosphite, antimicrobial activit

Designing an Adversarial Model Against Reactive and Proactive Routing Protocols in MANETS: A Comparative Performance Study

Mobile ad-hoc networks are self-organized infrastructure less networks that consists of mobile nodes, which are capable of maintaining and forming the network by themselves. Recently, researchers are designed several routing protocols on these networks. However, these routing protocols are more vulnerable to attacks from the intruders, which can easily paralyze the operation of the network due to its inherited characteristics of MANETS. One such type of attack is wormhole attack. Because of its severity, the wormhole attack has attracted a great deal of attention in the research community. This paper compares reactive and proactive routing protocols in adversarial environment. Specifically, wormhole attack is applied to these routing protocols to evaluate its performance through simulation. Comprehensively the results shows the comparative performance of these protocols against wormhole attack is hard to detect and easy to implement

Synthesis and Antimicrobial Activity of 3-[(4-Substituted) (2-oxo-1,3-oxazolidin-3-yl) phosphoryl]- 1,3-oxazolidin-2-ones

3-[(4-Substituted) (2-oxo-1,3-oxazolidin-3-yl)-phosphoryl]-1,3-oxazolidin-2-ones (4a–j) were synthesized through a two-step process. Bis-(2-oxo-1,3-oxazolidin-3-yl)-phosphonic chloride (2) prepared by the reaction of two moles of oxazolidin-2-one (1) with phosphorus oxychloride in dry tetrahydrofuran in the presence of triethylamine and treatment with various heterocyclic aromatic and aliphatic amines under the same experimental conditions afforded the title compounds (4a–j). They were characterized by elemental analysis, IR,NMR(1H, 13Cand 31P) and mass spectroscopy. Their antimicrobial activities were also evaluated.Keywords: 3-[(4-Substituted) (2-oxo-1,3-oxazolidin-3-yl)-phosphoryl]-1,3-oxazolidin-2-ones, oxazolidin-2-one, bis-(2-oxo-1,3-oxazolidin-3-yl)-phosphonic chloride, antimicrobial activity, spectral studie

6-Bromo-2-(4-nitro­phen­oxy)-3-(1-phenyl­ethyl)-3,4-dihydro-1,3,2-benzoxaza­phosphinine 2-oxide

In the title compound, C21H18BrN2O5P, the six-membered oxaza­phosphinine ring is in a twist-boat conformation. One of the phosphoryl O atoms is in an equatorial configuation while the other is axial with respect to the oxaza­phosphinine ring. The mean planes of the benzene ring to which the nitro group is attached and the phenyl ring form a dihedral angle of 83.5 (1)°. In the crystal structure, weak inter­molecular C—H⋯O hydrogen bonds link the mol­ecules into chains along [100]

2,4,8,10,13-Penta­methyl-6-phenyl-13,14-dihydro-12H-6λ5-dibenzo[d,i][1,3,7,2]dioxaza­phosphecin-6-thione

In the title compound, C25H28NO2PS, the cyclo­decene ring exhibits a crown conformation. The two dimethyl­benzene rings which are fused symmetrically on either side of the ten-membered ring, make dihedral angles of 20.2 (1) and 18.0 (1)°. The phenyl ring substituted at P is perpendicular to the heterocyclic ring, making a dihedral angle of 88.4 (1)°. The crystal structure is stabilized by very weak intra­molecular C—H⋯O hydrogen bonding

Postmastectomy chest wall radiation of left-sided carcinoma breast - a dosimetric comparison between electrons and photons

Background: For carcinoma breast patients requiring post mastectomy radiation therapy (PMRT), tangential photon beam (PB) is commonly used technique. The physical nature of electrons results in sharp dose fall off and reduces organs at risk (OAR) doses. Aim of the present study is to compare the coverage of chest wall and doses received by OARs – heart and lung between electron and photon beam plans in left sided breast cancer patients requiring PMRT.Methods: This study was done in 22 left sided carcinoma breast patients treated at GSL Medical College between May to December 2017. Both tangential PB plans and electron beam (EB) plans were generated on simulation computed tomography (CT) for each patient and both plans were compared. A dose of 50 Gy was prescribed to planning target volume (PTV) in 25 fractions.Results: The PB plans provided superior homogeneity index (HI) and conformity index CI compared to the EB plans (p<0.05). There was significant difference in favour of electron-beam plans for mean heart dose (p=0.0312), V25 Gy (p=0.029), V45 Gy (p=0.001) and V20 Gy of left lung (p=0.042). There was no significant difference in mean lung dose.Conclusions: Dosimetric data from this study suggests that PMRT with the electron beam can reduce doses to the heart and left lung with acceptable target coverage. It needs further research in the clinical setting